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Product Description
GW501516 also known as Cardarine is a fascinating compound that was first developed in the early 1990s. Cardarine has gotten popular among competitive athletes and it is used as a unique and potentially powerful SARM (Selective Androgen Receptor Modulator). That's because Cardarine has an extremely positive impact on metabolism and burning fat.
How does GW501516 Work?
Cardarine mechanisms are very similar to those of SARMs. This chemical allows the body to help regulate fatty acid metabolism which is absolutely amazing.
Cardarine (GW501516) is the most selective and potent Peroxisome Proliferator-Activated Receptor delta (PPARδ) agonist that has been demonstrated to be 1,000-fold more selective in comparison to existing subtypes. In obese primates, GW501516 increases high density lipoprotein cholesterol and apolipoprotein A-1 specific reverse cholesterol transport. GW501516 is therefore a model compound for a new type of obesity therapeutic, as well as a selective pharmacological tool for understanding lipid metabolism.
Benefits of GW501516
There are multiple benefits you can expect from Cardarine:
1 Increase fat burning
Cardarine can be used by those who are already lean or those who are obese in both genders. It increases glucose uptake by changing how the body treats nutrients, drastically reducing how fat is stored. This translates to a lowering of body fat whether the person alters their diet or not, although in studies those that did eat better had much more pronounced results..
2 Help with Muscle Growth
Since Cardarine can activate PPAR-delta pathways, it can also improve strength endurance. One study showed that the compound might increase muscle fibers associated with peak physical performance.
3 Protect heart and blood vessels
Evidence suggests that taking Cardarine might actually influence the way our blood vessels work. A study done on mice showed that it can prohibit oxidative damage that happens in blood vessels. This is in addition to boosting vessel-relaxing nitric oxide which helps protect blood vessels from the build-up of plaque in the arteries.
4 Minimize damage to the liver
Since the body' blood sugar levels are lower, Cardarine protects this vital organ from the bad effects of a diet with high levels of fructose and other sugars. One study on mice found that it actually improved non-alcoholic liver disorders. However, researchers say that very controlled short-term use of Cardarine proves to have the best effect on the liver.
5 Lower the risk for kidney disease
While research on this area is still in its early stages, there are signs that it can lower MCP-1 expression, which is one of the factors in the development of this dreaded condition.
The right dosage of GW501516
There are a lot of different opinions on the most optimal Cardarine dosage.
During clinical studies, researchers used dosages of 2.5 mg to 10 mg per day for 12 weeks at a time. Bodybuilders and fitness enthusiasts will use anywhere from 10 to 20mg of Cardarine per day.
No one has reported any ill effects from long-term use of Cardarine. However, stick to the maximum dose of 20 milligrams a day.
Popular stacks
Cardarine (GW-501516) can be used by itself at 10-20mgs a day. It also can be added at a dosage of 10-20mgs a day to both anabolic steroid stacks and SARM's stack.
Anabolic Steroids
Stacking it with the harshest anabolic steroids(especially Trenbolone) is a wise choice. Since it helps offset the negative endurance issues. It also will help with your lipid health too. Others like to stack it in with cutting cycles such as Winstrol, Turinabol, Anavar, Masteron.
Other SARMs
If you want to avoid anabolic steroids, and choose to run a mild fat burning stack. You can use it with RAD140 Testolone or S4 Andarine for fat loss. It also stacks well with other compounds like Ligandrol LGD4033-Anabolicum and MK2866 Ostarine for both fat loss and endurance benefits.
Potential Side-effects
There is not a lot of information available on the Cardarine side effects. I had done my research and was unable to find any user review that experienced negative side effects from Cardarine. There are many athletes who have used the drug for years with no adverse issues reported, although we do recommend you cycle off the drug every 3 months to give the body a break.
Half-life and detection times
The half-life is around 24 hours, so once a day dosing is perfectly fine. Some users like to take it about 3 hours before their exercise. Detection times are unknown but the consensus seems to be around 3-4 weeks.
Conclusion
GW501516 is one of the most widespread compounds in the bodybuilding community which has positive impact on performance, endurance, fat loss, and overall health. Even athletes turn to this compound to boost their performance and maximize gains. If that many people have tried it and experienced the results, it is a much safer buy than a new, “trendy” but largely untested supplement.
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